Category D agents have proven teratogenic potential but may, under certain circumstances, be indicated. Prior to using any category D agent, providers should perform a careful review of indications, duration of therapy, all potential.effects, and all potential alternatives to the proposed therapy.
In addition,patients should be informed of these considerations, allowing for informed con-
sent to the proposed therapy. Category X medications have proven teratogenic potential and use should be avoided in pregnancy
Proven Human Teratogens