PharmD Info

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Outcomes Measures, Pharmacoeconomics and Pharmacoepidemiology, Ad-Hoc Data Source, Record Linkage System, Cost effective analysis.
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Life year gained (LYG) is a measure used in pharmacoeconomics to estimate the value of a medical intervention or treatment. It is a measure of the number of years of life gained by a patient as a result of a specific treatment, compared to the expected number of years of life without the treatment.

To calculate LYG, we need to know the expected remaining years of life for a patient before and after the treatment. We can use life expectancy tables or other relevant data sources to estimate the expected remaining years of life. Then, we compare the expected remaining years of life before and after the treatment to determine the LYG.

Here's an example:

Let's consider a hypothetical study that evaluated a new treatment for breast cancer in women. The study followed two groups of women over a five-year period: one group received the new treatment, and the other group received the standard treatment. At the end of the study, it was found that the women who received the new treatment had a higher survival rate than those who received the standard treatment.

To calculate LYG for the new treatment, we would need to estimate the expected remaining years of life for the women in both groups. Let's say that the expected remaining years of life for women with breast cancer is 10 years without treatment, and that the women who received the standard treatment had an average survival rate of 6 years. However, the women who received the new treatment had an average survival rate of 8 years.

To calculate the LYG for the new treatment, we would subtract the expected remaining years of life without treatment (6 years) from the expected remaining years of life with the new treatment (8 years), giving us an LYG of 2 years. This means that the new treatment resulted in an average of 2 extra years of life for the women who received it, compared to the standard treatment.

In summary, LYG is a measure used in pharmacoeconomics to determine the value of medical interventions or treatments. It is calculated by comparing the expected remaining years of life before and after a treatment, and it can be used to evaluate the cost-effectiveness of different treatment options.
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