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Pharmacokinetics - Unit III B Pharm Notes - Protein Binding, Volume of Distribution, Compartment Models - One and Two IV Bolus and Infusion,

Significance of plasma drug concentration measurement

Significance of plasma drug concentration.pdf

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Compartment model-Definition and scope.

Compartment Modelling.pdf

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Pharmacokinetics of drug absorption - Zero order and first order absorption rate constant using Wagner - Nelson and Loo- Reigelman method

PK of Drug Absorbtion.pdf

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Volume of distribution and distribution coefficient

Volume of Distribution.pdf

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Compartment kinetics - One compartment models.

One Compartment - IV Bolus.pdf

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IV infusion one compartment open model.pdf

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Compartment kinetics - Two compartment models.

Two Compartment MOdel.pdf

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Curve Fitting - Download Here


Clearance concept, Mechanism of renal clearance, clearance ratio, determination of renal clearance.

Clearance concept.pdf

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Hepatic clearance and elimination.pdf

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Non-linear pharmacokinetics with special reference to one compartment model after 1. V drug administration, Michaeles Menten Equation, detection of non-linearity (Saturation mechanism)

Non linear pharmacokinetics with special reference.pdf

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